We’re not your typical comedy club. No overpriced drinks, no corporate vibe—just great comedy in a laid-back, fun setting. We produce indie shows, which means we do things our way: booking the best local talent, creating a space that’s welcoming and unpretentious, and making every show feel like the kind of night out you’ll be talking about for weeks.
This isn’t just another event on your calendar—it’s an experience. A party with jokes, a room full of laughter, and a reminder that sometimes the best nights out are the ones that feel a little off the beaten path. Come join us and see what makes our shows so special. Click here if you want to have fun!
What is Best Medicine Comedy?
Can I perform?
As much as we love watching people take their shot at standup comedy, we want to guarantee our audience gets the best show possible so all of our shows are booked ahead of time and we only book comics we have seen do well consistently.
However, we love our local comedy community and want to help new comics get a leg up so we’re always looking for breakout stars at our local open mics. If you’re interested in an open mic in San Francisco then you can find them by going to the Bay Area Comedy Network on Facebook.
